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Inside TRIAD

A laboratory setup with test tubes, pipette tips, pipettes, and a Dog Aging Project box with a dog image, all arranged on a white surface with a tiled wall in the background

Scientific Results: Test of Rapamycin in Aging Dogs (TRIAD): study design and rationale for a prospective, parallel-group, double-masked, randomized, placebo-controlled, multicenter trial of rapamycin in healthy middle-aged dogs from the Dog Aging Project

Published on December 22, 2025

This paper describes the TRIAD clinical trial, which is part of our ongoing work to understand healthy aging in dogs.

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Collage of pics of the three TRIAD Graduates, dogs. Two photos with a group of people sitting with a dog, and one photo of a dog sitting on the floor.

TRIAD Tails: Graduate Owners Share Their TRIAD Journey

Published on October 6, 2025

Three of the earliest participants in the Test of Rapamycin in Aging Dogs (TRIAD) clinical trial had a common reason for enrolling their aging companion pet in the study: wanting to enhance their dog’s quality as well as quantity of life.

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Thin Line Abstract Shapes in the background with a circle that has a group of big dog graphics in the middle. With the TRIAD logo on the right bottom corner (dog outline with a heart on the chest and an atom as a brain)

Inside TRIAD: A Closer Look at the TRIAD Cohort

Published on October 28, 2024

The TRIAD clinical trial is a nationwide, double-blind veterinary clinical trial. This means half the dogs will receive the medication under study, and half will receive a placebo. In this trial, we will study the effects of the medication rapamycin.

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Dog outline with heart and atom as a brain

Inside TRIAD: A Deeper Dive into the Test of Rapamycin In Aging Dogs

Published on October 24, 2024

In the TRIAD study, we hope to evaluate the safety, efficacy, and potential side effects of rapamycin in dogs, leading to improved veterinary care of senior dogs and contributions to the understanding of human aging.

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Inside TRIAD: Introducing the Test of Rapamycin in Aging Dogs

Published on September 20, 2023

Many of the insights the Dog Aging Project gathers are through its surveys and activities; however, we also gain valuable information from the veterinary electronic medical records (VEMRs) that we receive. Submission of a VEMR is not necessary to enroll in the Dog Aging Project longitudinal observational study, but some of our smaller cohorts like Precision and TRIAD do require eligible VEMRs for consideration.

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Scientific Results: Purpose, Partnership, and Possibilities: The Implementation of the Dog Aging Project Biobank

Published on February 24, 2023

In this paper, we describe the partnership between the Dog Aging Project and the Cornell Veterinary Biobank (CVB) at the Cornell University College of Veterinary Medicine to create the Dog Aging Project Biobank, a resource that stores and distributes biospecimens collected from Precision and TRIAD cohort participants.

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